Can anyone answer the following questions please? Couldnt answer..so..I need ur help!!!?
Q.8 A. A physician removed a piece of liver and had it examined under
the light microscope. The ensuing report indicated that many
hepatocytes (liver parenchymal cells) contained clear droplets. Some
of the droplets were so large that the nuclei were pushed off to one
side producing a "signet ring" appearance.
a. What was the condition that caused these changes?
b. Could the cells return to normal if the cause of the change was
removed?
I`ve got the questions from the following website:
http://www.pmc.edu.pk/sendup3.htm
thanx alot...!!!
This is known as Fatty liver disease.
Fatty liver disease has many different causes:
alcohol consumption, certain medications like
steriods, diabetes, insulin resistance,
weight gain, malnutrition, high cholesterol/triglyceride
levels, hereditary conditions, metabolic disorders
and others.
The fat inside the liver can cause pressure in the
liver. The fat can push the nucleus of the liver
cell out of position. If the liver cells become damaged
in the process, the immune system of the body
responds to this damage and can cause inflammation
to also develop in the liver. The liver is surrounded
by a membrane capsule...even so, this will cause
the liver to enlarge in size. It has now gone from
being Simple Fatty liver to Steatohepatitis.
Steato means fat, hepat means liver, and itis means
inflammation.
If the cause can be stopped: like stop drinking
alcohol, change to different medications or
stopping them, losing weight and other things
that pertain to the causes...the fat may leave the
liver and the liver cells can heal.
However, if this cannot be done, the pressure
in the liver from the fat and the inflammation
will lead to the liver cells dying off and forming
scar tissue in the liver that blocks the flow of
blood...this is then irreversible and a progressive
disease known as Cirrhosis of the liver.
Here is a link that explains about this:
http://en.wikipedia.org/wiki/Fatty_liver
http://www.medicinenet.com/fatty_liver/article.htm
http://www.aafp.org/afp/20060601/1961.html
So the answer would be Fatty liver disease and
yes, in some circumstances, the cells may return
to almost normal.
I hope this information is of some help to you.
Best wishes
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